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Although cellular abnormalities in the initiating cells of kidney stone may occur in the pRTECs, both Randall's plaque and plug occur in the more distal renal tubules, and thus the links between pRTECs and more distal events remain unclear

The decision to modify or discontinue GLP-1 therapy should always be made in consultation with your prescribing clinician, weighing the therapeutic benefits against the impact of side effects on quality of life

Researchers noted multiple study limitations, including use of records from health care organizations within the federated health research network TriNetX that may not be nationally representative, they wrote

doi:10.1073/pnas.032539299 Wakselman S, Bechade C, Roumier A, Bernard D, Triller A, Bessis A (2008) Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor