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Abnormal signs during this window: warmth exceeding ambient skin temperature, pain disproportionate to the injection itself, or immediate hives extending beyond the injection quadrant

Resveratrol inhibits urban particulate matter-induced COX-2/PGE2 release in human fibroblast-like synoviocytes via the inhibition of activation of NADPH oxidase/ROS/NF-kappaB

Large human meta-analyses and many randomized trials do not identify headache as a common or serious adverse event, but headaches are reported by a minority of users in some trials and postmarketing reports

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