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You can find genetic testing with various companies such as 23andme.com Its estimated that those with one mutation (heterozygous) decrease their ability to methylate by 30% and those with two mutations (homozygous) decrease their ability to methylate by 70%, making it virtually impossible to get adequate B12 from diet alone (19)

Further studies should investigate the differences and to distinguish between the G6PD variants, their combinations, and co-inheritance with other genes for bilirubin-related metabolism in favism and severe hyperbilirubinemia

The manuscript was written through contributions of all authors

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