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Participants treated with liraglutide (239), semaglutide (240), or tirzepatide (200) in the clinical trials had a percent reduction in fat mass approximately three times greater than the reduction in lean mass, leading to an overall improvement in body composition

On the other hand, it is worrisome that up to 42% of patients who were treated with GLP-2 analog in induction phase discontinued the study (Buchman et al

Glucagon-like peptide 1 receptor activation and platelet function: beyond glycemic control

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