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Journal of Experimental Medicine, 176 (4), 10531062

Current evidence on KD and the skin remains limited, focusing mainly on inflammatory skin diseases such as acne, psoriasis, and hidradenitis suppurativa (HS), as well as cutaneous melanoma

A practical heuristic: if youre set on using a modified form, the more conservative middle-ground protocols (1 mg/day for 20 days for N-acetyl amidate, or 1-2 mg for amidate alone) sit closer to the dose math that would be theoretically equivalent to the base epithalon protocols if the modifications deliver something like 5-10x bioavailability improvement

Patience here protects your investment