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A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%

Medical Image Analysis 97:103231

Figure 8 4 Discussion In this study, using clinically relevant rat kidney transplant models, we demonstrated that TB001 exerts multiple beneficial effects on graft outcomes, including reducing fibrosis and improving graft function