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62 Despite these indications of tumor sensitivity to insulin, it is not clear to which extent the modulation of insulin and IGF-1 levels is able to influence the proliferation of progressive cancers that have become self-sufficient in growth and metabolic signals as illustrated for example by: (i) expression of insulin-independent glucose transporter isoforms

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Con respecto al efecto pro cognitivo, deberamos esperar estudios confirmatorios", sigue el psiquiatra

An embodiment of present invention provides a process for purification of compound of forumula-13, comprising subjecting a solution of compound of formula- 13 to RP-HPLC purification by using buffer solution as mobile phase- A and acetonitrile as mobile phase-B