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One more antioxidant factor imperative for healthy development of the ovarian follicle is transferrin (iron-chelating glycoprotein) that impedes the generation of ROS [91]

Mitochondrial dysfunction has been implicated in the altered metabolic flexibility in such conditions (76, 77)

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Summary: Amino acids, particularly L-arginine and L-citrulline, may provide modest benefits for mild to moderate erectile dysfunction, but evidence is mixed and they are not recommended as first-line treatment in UK guidance