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The drug has a long half-life, which means it can be administered monthly or less frequently, giving the drug the potential to improve adherence and long-term weight control, according to Jay Bradner, executive vice president of research and development at Amgen

Lee, Clapp, Martial, Weiner, "Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression," Endocrinology, 139(9): 3696-3703, 1998

Gamble JM, Chibrikov E, Midodzi WK, et al

Vyvanse and drugs that make urine more acidic Vyvanse may interact with certain drugs that can make urine more acidic