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Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons

Graves hyperthyroidism is caused by autoantibodies to the thyroid-stimulating hormone receptor (TSHR) that act as agonists and induce excessive thyroid hormone secretion, releasing the thyroid gland from pituitary control

The nine essential amino acids are: Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Threonine Tryptophan Valine Youll notice that L-arginine and L-citrulline are absent from the list, meaning theyre present in your body

We next considered the potential role of neoantigens resulting from SNVs in early disease by predicting neoantigens for patient-specific HLA-A, -B and -C alleles using NetMHC4.0 31,32 (see Supplementary Methods) and examining the loss of these predicted neoantigens due to LOH in late disease