Caroline was working concurrently with her GP and endocrinologist, and experiencing ongoing symptoms including feeling very fatigued, heart palpitations, body tremors, hair loss, insomnia, heartburn, diarrhoea, an ongoing cough, swollen thyroid, sudden irritability, and mood swings
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Statistically, these changes were distinct when compared with placebo
Secondary outcomes included nonfatal MI, nonfatal stroke, HHF and renal composite outcome, defined in most trials as a composite of progression to end-stage renal disease or a sustained decrease of at least 40% in estimated glomerular filtration rate (eGFR)