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Inactivation of the proteasome system in fibroblast cells is related to the generation of singlet oxygen, protein oxidation and transcriptional agents that regulate MMP-1 expression activation (31)

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NCT03352557) ( Discussion Post-COVID complications pose a significant public health burden, with a recent study from CDC reporting its prevalence at between 20 and 25% among COVID-19 patients ( The extensive literature review above revealed the tau deposits in the brain by examining the tissue samples from autopsies of COVID-19 patients compared to controls