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This hypothesis suggests that by identifying deregulated metabolic pathways, new diagnostic targets can be identified, allowing for the implementation of optimized treatments, including during fetal life, with the aim of providing protective effects for the brain development of individuals with T21 (Fayal Guedj, Bianchi, and Delabar 2014)

60,72 Other identified side-effects of NAC include nausea, vomiting, diarrhea or constipation, and rarely fever, headache, drowsiness or hypotension