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The TSA conducted in our study revealed that the limited number of participants may have contributed to the non-significant findings for all-cause mortality

1 2 "Cellular uptake and intracellular trafficking of long chain fatty acids"

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Acute exposure to homocysteine (50 M1 mM for 24 h) led to activation of the Nrf2 pathway (with a peak expression of Nrf2 3 h after Hcy administration), increased expression of genes encoding antioxidant enzymes, including NQO1, CAT, SOD2, HMOX1, and GPX1, and a concomitant decrease in ROS and alleviation of oxidative stress [56]