Its mechanism involves interaction with GHRH receptors, activation of GH secretion, and downstream IGF-1 production
Current research does not show that BPC-157 directly raises circulating testosterone or growth hormone levels in healthy adults
Ligand binding triggers receptor-mediated endocytosis or other forms of cellular internalization, which not only enhances drug uptake but can also modulate downstream signalling pathways that influence therapeutic outcomes
Zhang LJ, Chen SX, Guerrero-Juarez CF, Li F, Tong Y, Liang Y, Liggins M, Chen X, Chen H, Li M, Hata T, Zheng Y, Plikus MV, Gallo RL (2019) Age-related loss of innate immune antimicrobial function of dermal fat is mediated by transforming growth factor beta