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After consideration of the public comments we received, we are finalizing our policy without modification for CPT code 78803

Joint Pain and Stiffness: By promoting the synthesis of cartilage-protecting proteoglycans and reducing localized joint inflammation, SAMe can significantly improve joint comfort and mobility, particularly in osteoarthritis and fibromyalgia

Figures were drawn using KingDrawPc V3.0.2.20 (Qingdao Qingyuan Precision Agriculture Technology Co., Ltd., Qingdao, China), GraphPad Prism 9.0 (GraphPad Software, San Diego, CA, USA), and Adobe Illustrator 202226.0 (Adobe Systems, San Jose, CA, USA) for graphic illustration