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[ In general, it is considered that serum UA values between 3.5 and 7.2 mg/dL (0.210.43 mmol/L) in adult males and postmenopausal women and between 2.6 and 6.0 mg/dL (0.16-0.36 mmol/L) in premenopausal women are normal in many countries

Peroxiredoxin 1 has specifically been shown to protect PTEN from oxidative inactivation and may play an essential role in tumorigenesis by limiting the activation of growth and survival pathways (53)

Firstly, we discussed the epidemiology and various risk factors such as genetic mutations ( BRCA1/2, TP53, PTEN ), hormonal influences, several lifestyle risk factors (obesity, smoking, etc.), and environmental factors (chemical exposure, air pollutants, etc.)

Zhang H, Wang M, He Y, Deng T, Liu R, Wang W, et al