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In a nitroglycerin-induced migraine model in rats, we have observed similar iron accumulation in serum (unpublished data)

In the SCALE Obesity and Prediabetes trial (Pi-Sunyer et al., NEJM 2015), participants receiving Saxenda alongside lifestyle modification achieved mean weight loss of approximately 8% of initial body weight, compared with 2.6% in the placebo group

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Higher doses reached that plateau later in the trial. In a 112-week step-down trial, participants maintained 21.9% loss on the top dose, 16.6% after stepping down to 5 mg, and 9.9% on placebo