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The interaction of GLP-1 with the GLP-1R increases insulin secretion in response to glucose and decreases glucagon levels through increasing intracellular cyclic adenosine monophosphate (cAMP) [7]

Ferro EG, Michos ED, Bhatt DL, Lincoff AM, Elshazly MB

The Gut: a key to the pathogenesis of type 2 diabetes