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Cell Mol Immunol 18(5):11411160
Eine weitere Stoffklasse, deren Vertreter ebenfalls ber den Inkretin-Effekt wirken, sind die Gliptine, die durch Hemmung des Enzyms Dipeptidylpeptidase 4 (DPP-4) den Abbau von GLP-1 und GIP blockieren
These abnormalities can be eliminated by either reexpressing WT TANGO2 or CRISPR correction of the specific mutation, supporting the validity of these models
However, this process depends on the availability of certain cofactors, including: Vitamin C Vitamin B6 Vitamin B3 (niacin) Iron A deficiency in these nutrients can impair the body's production of L-carnitine
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