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doi: 10.1016/j.biopha.2022.113611 35 LiNWangYWangXSunNGongYH

So for every glucose 6 Phosphate that gets into the HMP Shunt, 2 NADPH is formed

Pancreatic glucagon is a 29amino acid peptide that regulates glucose homeostasis via gluconeogenesis, glycogenolysis, and lipolysis and is counter regulatory to insulin