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For a description of the statutory authority for and existing policies pertaining to the cost performance category, we refer readers to 414.1350 and 414.1380(b)(2) and the CY 2017 Quality Payment Program final rule (81 FR 77162 through 77177), CY 2018 Quality Payment Program final rule (82 FR 53641 through 53648), CY 2019 PFS final rule (83 FR 59765 through 59776), CY 2020 PFS final rule (84 FR 62959 through 62979), CY 2021 PFS final rule (85 FR 84877 through 84881), CY 2022 PFS final rule (86 FR 65445 through 65461), CY 2023 PFS final rule (87 FR 70055 through 70057), CY 2024 PFS final rule (88 FR 79339 through 79349), and CY 2025 PFS final rule (89 FR 98390 through 98408)

Large-scale human studies have not identified a clear dose-response relationship or consistent temporal pattern that would support a direct causal link

Consistency is the most important factor in seeing the benefits of any wellness routine

Sleep Deprivation: Insufficient or poor-quality sleep disrupts the bodys antioxidant defenses, including glutathione