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public comment period closes June 29, 2026 - large-scale 503B compounding pathway under active regulatory review 503A patient-specific compounding: operates under a separate legal framework independent of shortage-list status

Shah says he would caution people with type 1 who are not overweight to avoid taking a GLP-1 drug, since retrospective studies have found that this group tends to have more gastrointestinal side effects, which may lead them to stop using the drug

Semaglutide delays gastric emptying by activating GLP-1 receptors in the stomach and pylorus, slowing the rate at which food and oral medications leave the stomach and enter the small intestine where absorption occurs

Together, these functions help to control blood sugar levels