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61 Concurrently, persistent activation of the sterol regulatory element-binding protein 1c (SREBP-1c) pathway in hepatocytes promotes de novo lipogenesis, further increasing lipid deposition

It plays a crucial role in various physiological processes and is primarily taken as a supplement because it is a powerful antioxidant that helps protect cells from oxidative stress and damage caused by free radicals

Normally, very large amounts of quercetin are nutritionally required to achieve some its health benefits because it's not very "bioavailable" or easy for the body to take up and use, since it's not water-soluble

Hammadeh, M., Hamad, M., Montenarh, M