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Glucagon and insulin cooperatively stimulate fibroblast growth factor 21 gene transcription by increasing the expression of activating transcription factor 4

Finally, to examine the effect of intermittent or continuous GLP-1R receptor stimulation, the impact of genotype was characterized for both short and long-acting agonists, data from all 5 studies were pooled (Additional file 2: Fig

Effects of low extracellular sodium on proliferation and invasive activity of cancer cells in vitro

In rodent models, a number of studies have found that GLP-/GIP dual agonists group mice have reduced fat mass, decreased circulating cholesterol, and lost weight, which has excellent weight loss effect