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Extended-release metformin, taking the medication with meals, avoiding high-fat foods, and starting with a low dose can greatly reduce gastrointestinal side effects, including diarrhea, nausea, and stomach discomfort

Pre-diabetes is caused by either the inability of the pancreas to produce sufficient insulin, or the inability of the body to respond appropriately to insulin- insulin resistance

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A 2013 study in Emerging Infectious Diseases found that immunity to norovirus may be as short as four years for adults, although some people may have protections for up to eight years