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Understanding which combinations make mechanistic sense and which should be avoided is important for safe and effective protocols

Clinical improvement was also observed in oxidative stress markers, with improvements in methionine levels (p=0.05), homocysteine levels (SAH, p=0.007) and the ratio of S-adenosylmethionine (SAMe) to SAH (p=0.007), indicating improvement with methylation at the cellular level and a decrease in oxidative stress in the body 2

The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount