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The lower rate of cardiac events included a reduction in the adjusted risk of death and a reduction in heart attacks

We're talking like five to 15% of a person's body weight in a year, and we think these GLP-1 like drugs work in part by traveling to the brain and triggering these molecular switches in parts of the brain that control appetite and hunger, they make people's brains feel full and they eat less

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[27] Clinical significance [edit] Melanoma - Cancer affecting melanocytes Melanocytic tumors Melanocytic tumors of uncertain malignant potential Vitiligo - Decreased number of melanocytes due to autoimmune destruction causing decreased melanin Albinism - Normal number of melanocytes, but decreased melanin production due to decreased tyrosinase activity or defective tyrosine transport Melasma (Chloasma) - Patchy hyperpigmentation of the skin Normal number of melanocytes with increased melanin production causing hyperpigmentation