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a,b,c Mechanistically, the At LDOX catalysed hydroxylation of 3,4- cis -leucocyanidin ( 6 ) may result in hydroxylation products at C 2 ( a ), C 3 ( b ) or C 4 ( c )

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While curcumin supplementation in dogs appears to significantly reduce the expression of genes associated with inflammation, 53 its overall effect on pain and mobility in dogs with osteoarthritis has produced variable results, exhibiting improvements in subjective pain assessments in some cases of dogs with osteoarthritis, but not exhibiting reliable objective improvements in mobility