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Amanita species have various biological activities like antitumor, pesticidal, cytotoxic, antioxidant, anticancer, antibacterial, acetylcholinesterase, esterolytic, antiviral, activity, anti-larvicidal, antifungal, anti-inflammatory properties (Sevindik et al., 2019)

Class 4 shows very mild or no deficiency of the G6PD enzyme

Furosemide and rosuvastatin were given as single doses, whereas the OCs were dosed to steady state in order to provide clinically relevant exposures while taking pharmacokinetics and tolerability of the compounds into consideration