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Once at the IGF-1 receptor it triggers the same downstream anabolic cascade as IGF-1 PI3K/Akt and MAPK signaling that promotes protein synthesis and satellite-cell activity but its poor binding-protein affinity also means rapid clearance [3]
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Health professionals recommend that individuals at high risk of deficiency, such as those following a vegetarian or vegan diet, take vitamin B12 supplements to prevent folate deficiency anaemia
Individual results vary based on starting weight, baseline metabolic health, diet adherence, exercise consistency, and sleep quality
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