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For healthy adults, the recommended dietary allowance for methionine plus cysteine is 19 mg/kg per day (1140 mg/day for a 60 kg adult) (93)

showed that GSH is required for cancer initiation partially because of the upregulated activation of the thioredoxin (TXN) antioxidant pathway and inhibition of both GSH and TXN pathway activation, synergistically inhibiting tumor growth 26

Its proposed mechanism centres on G-actin sequestering, cell migration and angiogenesis in preclinical work [5] [6]

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