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When I asked, in the previous article, whether the clinical community would build the practice around the evidence, I did not anticipate quite how quickly the evidence itself would begin to expand

Signs of Ozempic face include Sunken or hollow cheeks Hollow temples More visible wrinkles and fine lines Sagging skin around the jawline and neck Deeper lines around the nose and mouth A tired or aged appearance Hollows under the eyes These changes usually start showing up after someone loses 15 to 20 pounds, which can happen within 2 to 6 months of starting treatment

While injection-site irritation is well recognized, clinicians are increasingly observing broader skin changes in patients treated with semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)

In patients with T2DM and hepatic steatosis, Cuthbertson et al