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Reduced food intake can make it difficult to meet protein, fluid, and micronutrient requirements, particularly for nutrients such as: iron calcium magnesium zinc vitamins B12 and D Maintaining adequate protein intake approximately 1.2 to 1.5 grams per kilogram of body weight per day and participating in regular resistance training are important strategies for preserving muscle mass and physical function during weight loss

For providers, these developments require both immediate clinical adjustmentssuch as body composition monitoring and patient education updatesand longer-term strategic planning for oral formulations and combination therapies