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If acidosis of either form occurs, Janumet must be stopped immediately and other appropriate corrective measures initiated

What to Expect When Switching: First 2-4 Weeks: Side effects may recur even if you tolerated the first medication well Nausea and GI symptoms are common during transition Appetite changes may feel different Weight loss may slow temporarily Weeks 4-12: Body adjusts to new medication Side effects typically improve Appetite suppression becomes consistent Weight loss resumes or accelerates (especially switching to tirzepatide) After 3 Months: Full effects of new medication apparent Can assess if switch was beneficial May adjust dose based on results and tolerance Switching Success Rates: Most patients successfully transition between medications

Take Control of Your Injury Today Post-injection pain and inflammation often occur after an intramuscular injection as the body reacts to the needle or medicine

Aklhaled and Butsch are with the Cleveland Clinic Foundation in Cleveland, Ohio