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Four groups of eight-week-old female BALB/c mice, were introduced by aerosol into the lungs with increasing dosages of GST-ETX

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The skin parameters were measured by corneometer (hydration), tewameter (TEWL), an Antera 3D system (wrinkles), and elasticity (cutometer) at baseline and day 42 and day 84 in the treatment groups ( n = 36 treatment