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20 Mez and colleagues evaluated available case series and grouped CTE symptoms into stages: Stage 1, attention loss and headache, Stage 2 depression and short-term memory loss, Stage 3 cognitive impairment, and Stage 4 poor verbal skill and aggression

However, it is not recommended for neonates due to the presence of benzyl alcohol

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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors