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Binding to mitochondrial proteins, especially in the context of glutathione (GSH) depletion, is critical because it disrupts the natural antioxidant functions of mitochondria and alters the ATP-synthase -subunit, impairing ATP production [93]

Although metformin is widely accepted as the first-line therapy for type 2 diabetes, its effects on cognitive outcomes have been inconsistent, Wu said

The reduction in muscle cross-sectional area without any reduction in strength likely reflects loss of intramuscular substrate (triglycerides, glycogen) rather than contractile proteins

Cathepsin L regulates oocyte meiosis and preimplantation embryo development