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The SGLT-2 inhibitor clinical trials included in this review suggest this class of medications may provide possible renoprotective effects as well

Tirzepatide versus semaglutide In the direct head-to-head comparison, the 1-year risk of the primary endpoint including all-cause mortality was 1.3% (95% CI 1.2% to 1.5%) for tirzepatide and 1.3% (95% CI 1.2% to 1.5%) for semaglutide, resulting in a risk difference of 0.0% (95% CI 0.2% to 0.2%) and an HR of 1.06 (95% CI 0.95 to 1.18) (Fig

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Because the medication is administered via a gradual titration schedulestarting at a low dose to minimize side effectsthe full hunger-suppressing impact typically builds over the first month as the concentration of the drug stabilizes in your system