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Along with those problems, medication errors made by GLP-1 providers and the patients taking them jumped from just over 2,000 reports in 2020 to over 25,000 in 2025, according to a data analysis by KFF, a national, nonpartisan health policy research organization

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[1] [2] Individual gastrointestinal sensitivity: Patients with pre-existing gastrointestinal conditions such as gastroparesis, irritable bowel syndrome, or functional dyspepsia may experience earlier and more severe symptoms

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