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It is implicated in the processes of tumor invasion and metastasis, and its elevated activity is often correlated with a reduction in patient survival times, highlighting its significance as a prognostic indicator in cancer (153)

This effect was abolished in Glp1r knockout mice, and hence, the improvement of l-arginine-stimulated glucose tolerance is dependent on this receptor (165)

Chandra J (2009) Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies