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Both intermittent dosing schedules (injections on specific days) and continuous daily administration showed benefits, suggesting some flexibility in protocol design

A higher Bcl-2/Bax ratio means cells are more likely to survive

observed a marked increase in ACSL4 expression in a heart failure model induced by TAC in mice, and ACSL4 overexpression in cardiomyocytes exacerbates the cardiac dysfunction triggered by pressure overload through ferroptosis