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Simultaneous quantification of ligustilide, dl-3-n-butylphthalide and senkyunolide A in rat plasma by GC-MS and its application to comparative pharmacokinetic studies of Rhizoma Chuanxiong extract alone and Baizhi Chuanxiong Decoction

Lipid peroxidation products including malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) form adducts with cellular proteins, generating neo-epitopes that activate immune cells and enhance antigen presentation (101)

Low B12 levels contribute to increased levels of homocysteine, an amino acid that, in excess, can damage blood vessel walls and increase the risk of heart disease

Marx CE, Keefe RS et al (2009)