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A hallmark of ferroptotic initiation and execution is the upregulated peroxidation of phospholipid-bound polyunsaturated fatty acids (PUFAs) within cellular membranes, a process facilitated by labile iron pools (LIPs) and amplified through autocatalytic radical reactions (13,14)
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When the body loses more fluid than it takes in, urine becomes more concentrated, allowing minerals and salts to crystallise more easily
These medications are most effective when integrated into a comprehensive weight management programme that includes dietary modification, increased physical activity, and behavioural support
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