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"But there's something about being 71 that gives you a perspective and the long view of appreciation that's unlike any other time in your life." Winfrey added that while she felt good at 40, being strong and healthy at 71 has been much more meaningful

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PT-141 results in increased production of nitric oxide (NO) synthesized from neuronal nitric oxide synthase (nNOS), with the NO activating soluble guanylate cyclase to catalyze the conversion of guanosine triphosphate (GTP, also called guanosine 5'-triphosphate) to cGMP