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doi: 10.3389/fcvm.2024.1446468 Received 09 June 2024 Accepted 21 November 2024 Published 16 December 2024 Volume 11 - 2024 Edited by Masanori Aikawa, Brigham and Women's Hospital and Harvard Medical School, United States Reviewed by Prabhash Kumar Jha, Brigham and Women's Hospital and Harvard Medical School, United States Satyesh K

Many have reported a reversibility of LCAC-mediated effects in ischaemia following normoxic reperfusion, suggesting direct enzymatic or ionic modulation by LCACs (Ruiz et al., 2017)