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How Belly Fat Lowers Testosterone and Raises Estrogen in Men: Aromatase Mechanism and Adverse Effects Additional Benefits of Tirzepatide Beyond Hormonal Balance Tirzepatide mimics two naturally occurring hormones GLP-1 and GIP that work together to support healthy metabolism

In December 2025, the FDA also expanded the Mounjaro indication to include paediatric patients aged ten and over with type 2 diabetes, following results from the SURPASS-PEDS trial

This promotes a feeling of fullness and may help with weight management

Evidence in T1D is limited to small, short-term, randomized clinical trials (RCTs) and a few observational studies focusing on surrogate outcomes such as glycemic control and weight loss 8,9,10,11,12