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Gut barrier protection Selective digestive tract decontamination (oral antibiotics targeting gram-negative bacteria) and microecological regulation (e.g., Akkermansia muciniphila supplementation) enhance intestinal tight junction protein expression, reducing endotoxemia and liver injury [66, 84]

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Of the evaluated statins, atorvastatin was the most frequently implicated in the development of cholestatic DILI (i.e., in eight of the eleven cases), 29,3134,3739 which is consistent with the findings of a retrospective study by Bjrnsson et al

Subtypes of atopic dermatitis: from phenotype to endotype