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Liraglutide has been shown to exhibit antioxidant and anti-inflammatory properties that reduce eNOS uncoupling and increase NO bioavailability, NO bioavailability is thereby maintained, endothelium-mediated vasorelaxation is preserved, and vascular remodeling and fibrosis are prevented

As described above, although resmetirom and semaglutide have different mechanisms, they both improved liver injury, as reflected by a decline in ALT and AST levels and liver hydroxyproline content