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On the other hand, extrinsic apoptosis is mediated by different molecules and ligands such as TNFR1-TNF, FAS-FasL, and TRAIL-DR4/DR5

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We provide evidence suggesting the possibility that sulfane sulfur species produced by 3-mercaptopyruvate sulfurtransferase and sulfide:quinone oxidoreductase are the actual mediators of the immediate antioxidative and cytoprotective effects provided by NAC